How to create and manage signatures in Apple Mail A signature is automatically placed at the end of each e-mail message. Let's see how to create one. Go to Mail. Click Preferences. Select the Signatures tab. To delete a signature, select it. And click the minus sign. Clicking OK will permanently remove the signature. This cannot be undone. Let's add a new signature by clicking the plus icon. Give this signature a name. Click in this box and type to edit the signature. It's possible to create different signatures for each e-mail address you have added to Mail instead of using the same one for all accounts. Click an account. Now add a new signature as we did in the last step. Set the default signature to use for this account. That's it! Now you know how to create and manage your signatures.